ASD Researchers at UNC

Professor, Department of Pharmacology/Eshelman School of Pharmacy

Dr. Bryan Roth is the Michael Hooker Distinguished Professor in the Department of Pharmacology and Division of Chemical Biology and Medicinal Chemistry in the Eshelman School of Pharmacy. He is also the director of the NIMH Psychoactive Drug Screening Program.  Dr. Roth’s research interests include GPCR structure and function, synthetic neurobiology, and drug discovery.  The Roth Lab studies the structure and function of G-Protein coupled receptors (GPCRs).  He has worked with Drs. Ben Philpot and Mark Zylka to identify drug-like compounds for the treatment of autism spectrum disorders. This includes work with an animal model of Angelman syndrome, a neurodevelopmental disorder causes by inactivation of the Ube3a gene.